Computer-assisted cognitive behavior therapy (CCBT) and mobile applications (mobile apps) are two forms of digital health technologies applied to mental health. CCBT helps patients build core CBT knowledge and skills, while reducing traditional face-to-face sessions to about a third of the time typically spent in CBT. Mobile apps can provide elements of CBT, such as specific coping methods like breathing training, relaxation, and mood tracking. Although there is more efficacy data for CCBT, mobile apps can be used effectively to deliver quality service when a provider follows proper guidelines for selecting apps and engaging patients in their use. The objectives of this chapter are to: (1) Review the empirical support for CCBT and mobile apps, (2) Discuss features of some commonly used CCBT programs and mobile apps, and (3) Offer suggestions for using these methods in clinical practice especially as related to rural community needs.